Traditional machine learning algorithms use data from databases that are mutable, and therefore the data cannot be fully trusted. Also, the machine learning process is difficult to automate. This paper proposes building a trustable machine learning system by using blockchain technology, which can store data in a permanent and immutable way. In addition, smart contracts are used to automate the machine learning process. This paper makes three contributions. First, it establishes a link between machine learning technology and blockchain technology. Previously, machine learning and blockchain have been considered two independent technologies without an obvious link. Second, it proposes a unified analytical framework for trustable machine learning by using blockchain technology. This unified framework solves both the trustability and automation issues in machine learning. Third, it enables a computer to translate core machine learning implementation from a single thread on a single machine to multiple threads on multiple machines running with blockchain by using a unified approach. The paper uses association rule mining as an example to demonstrate how trustable machine learning can be implemented with blockchain, and it shows how this approach can be used to analyze opioid prescriptions to help combat the opioid crisis.