In recent years, tremendous success has been witnessed in Retrieval-Augmented Generation (RAG), widely used to enhance Large Language Models (LLMs) in domain-specific, knowledge-intensive, and privacy-sensitive tasks. However, attackers may steal those valuable RAGs and deploy or commercialize them, making it essential to detect Intellectual Property (IP) infringement. Most existing ownership protection solutions, such as watermarks, are designed for relational databases and texts. They cannot be directly applied to RAGs because relational database watermarks require white-box access to detect IP infringement, which is unrealistic for the knowledge base in RAGs. Meanwhile, post-processing by the adversary's deployed LLMs typically destructs text watermark information. To address those problems, we propose a novel black-box "knowledge watermark" approach, named RAG-WM, to detect IP infringement of RAGs. RAG-WM uses a multi-LLM interaction framework, comprising a Watermark Generator, Shadow LLM & RAG, and Watermark Discriminator, to create watermark texts based on watermark entity-relationship tuples and inject them into the target RAG. We evaluate RAG-WM across three domain-specific and two privacy-sensitive tasks on four benchmark LLMs. Experimental results show that RAG-WM effectively detects the stolen RAGs in various deployed LLMs. Furthermore, RAG-WM is robust against paraphrasing, unrelated content removal, knowledge insertion, and knowledge expansion attacks. Lastly, RAG-WM can also evade watermark detection approaches, highlighting its promising application in detecting IP infringement of RAG systems.