We study data poisoning attacks in the online setting where training items arrive sequentially, and the attacker may perturb the current item to manipulate online learning. Importantly, the attacker has no knowledge of future training items nor the data generating distribution. We formulate online data poisoning attack as a stochastic optimal control problem, and solve it with model predictive control and deep reinforcement learning. We also upper bound the suboptimality suffered by the attacker for not knowing the data generating distribution. Experiments validate our control approach in generating near-optimal attacks on both supervised and unsupervised learning tasks.