Fuzz testing has become a cornerstone technique for identifying software bugs and security vulnerabilities, with broad adoption in both industry and open-source communities. Directly fuzzing a function requires fuzz drivers, which translate random fuzzer inputs into valid arguments for the target function. Given the cost and expertise required to manually develop fuzz drivers, methods exist that leverage program analysis and Large Language Models to automatically generate these drivers. However, the generated fuzz drivers frequently lead to false positive crashes, especially in functions highly structured input and complex state requirements. This problem is especially crucial in industry-scale fuzz driver generation efforts like OSS-Fuzz-en, as reporting false positive crashes to maintainers impede trust in both the system and the team. This paper presents two AI-driven strategies to reduce false positives in OSS-Fuzz-Gen, a multi-agent system for automated fuzz driver generation. First, constraint-based fuzz driver generation proactively enforces constraints on a function's inputs and state to guide driver creation. Second, context-based crash validation reactively analyzes function callers to determine whether reported crashes are feasible from program entry points. Using 1,500 benchmark functions from OSS-Fuzz, we show that these strategies reduce spurious crashes by up to 8%, cut reported crashes by more than half, and demonstrate that frontier LLMs can serve as reliable program analysis agents. Our results highlight the promise and challenges of integrating AI into large-scale fuzzing pipelines.