The rise of ad-blockers is viewed as an economic threat by online publishers, especially those who primarily rely on ad- vertising to support their services. To address this threat, publishers have started retaliating by employing ad-block detectors, which scout for ad-blocker users and react to them by restricting their content access and pushing them to whitelist the website or disabling ad-blockers altogether. The clash between ad-blockers and ad-block detectors has resulted in a new arms race on the web. In this paper, we present the first systematic measurement and analysis of ad-block detection on the web. We have designed and implemented a machine learning based tech- nique to automatically detect ad-block detection, and use it to study the deployment of ad-block detectors on Alexa top- 100K websites. The approach is promising with precision of 94.8% and recall of 93.1%. We characterize the spectrum of different strategies used by websites for ad-block detection. We find that most of publishers use fairly simple passive ap- proaches for ad-block detection. However, we also note that a few websites use third-party services, e.g. PageFair, for ad-block detection and response. The third-party services use active deception and other sophisticated tactics to de- tect ad-blockers. We also find that the third-party services can successfully circumvent ad-blockers and display ads on publisher websites.